Incorporation of magnetic nanoparticles into polyurethane to fabricate organic-inorganic nanocomposites applicable for tissue engineering

The engineered polymers with controlled mechanical properties in surface are effective means for dissecting exogenous cues that act on stem and progenitor cells fate. Among other factors such as biological and biochemistry factors, physical properties of extracellular matrix surface effect on the fate of stem cells. So in conjunction with other factors, physical factors of polymeric scaffolds can be used to produce and repair tissues. Bio-mechanical properties of microenvironment can effect on self-renewal and differentiation of stem cells. However determination of stem cell fate, according to the bio-mechanical properties of substrates is a major challenge that can create new opportunities in tissue engineering and medicine field with innovations in stem cell-based applications