Evaluation and Comparison of Prostate & Rectum Radiation Absorbed dose in 3D Conformal treatments using Cobalt-60 Unit & Linac

سال انتشار: 1387
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 1,715

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شناسه ملی سند علمی:

ICMEDICALP08_009

تاریخ نمایه سازی: 19 شهریور 1387

چکیده مقاله:

OBJECTIVE: Radiation therapy is a good option for treating this cancer and new radiotherapy techniques has an essential role in prostate treatment. This Study was designed to evaluate the dosimetric parameters such as rectum dose, bladder dose, Integral dose (ID), Homogeneity Index (HI) and Conformity Index (CI) in both Conventional and 3D Conformal Radiotherapy (3D CRT) at three different energies: Cobalt-60, 6 MV and 18 MV . Materials and Methods: Computed tomography (CT) scans of pelvis of 27 patients were acquired and transferred to the RTDosePLAN treatment planning system. For each patient, 8 Conventional plans (3, 4, 5 and 6 Fields) and one 3D CRT plan were planned by in Cobalt-60 photon Energy, and then the same plans were performed by 6 MV and 18 MV Photon Energies . Results: By increasing the energy of beam relative to Cobalt-60 energy, rectum’s and bladder’s Dmean were decreased by 3 to 4% and 4 to 6%, respectively, bladder’s D3/3 and D2/3 to bladder were decreased by 26% and 8% for 6 MV and 58% and 20% for 18 MV. Increasing the photon beam energy decreased CI to 7% and 10%, 10% and 20% for ID and 3% to 4% for Dmax. CI and ID in 3D CRT decreased to 50% and 33% in comparison of Conventional RT . Conclusions: Compared with conventional treatment techniques, Conformal RT offered the most conformity in delivery of tumoricidal doses to the prostate while sparing dose to critical, uninvolved structures with Lower Integral Dose .

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نویسندگان

SA Vaezzadeh

Medical Physics Department, Tehran University of Medical Science, Tehran, Iran

M Allahverdi

Medical Physics Department, Tehran University of Medical Science, Tehran, Iran

H Nedaie

Radiotherapy-Oncology Department, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran

M Aghili

Radiotherapy-Oncology Department, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran