Survey the positive predictive value of laboratory findings in diagnosis of acute cholecystitis

Introduction: One of the most common surgical problems was acute cholecystitis that accurate and timely diagnosis to start of treatment and decreased mortality are needed. Due to contradictory results regarding diagnostic methods in acute cholecystitis, this study investigated the positive predictive value of laboratory findings in diagnosis of acute cholecystitis. Materials and methods: This cross-sectional study using all people records that had cholecystectomy with diagnosis of acute cholecystitis in Dezful large hospital in 1393 was performed. Laboratory findings included the number of leukocytes, levels of AST, ALT, alkaline phosphatase, direct and indirect bilirubin that compared with pathological findings as definitive diagnosis. Results: In this study 67 patient’s records with a mean age of 47.58 ± 17.36 years, 23 patients (%34.3) were male and 44 patients (%65.7) were female. Positive predictive value or sensitivity was %56.1 for WBC, %34.2 for alkaline phosphatase, %37.5 for AST, ALT (50%), direct bilirubin (%77.4) and % 62.1 indirect bilirubin. There was a direct correlation between age and the amount of direct bilirubin that was statistically significant (p=0.03) (r=0.37). But there was no significant correlation between age and other existing tests (P> 0/05). Conclusion: Due to the ease of access to liver enzymes and their values obtained in this study, they can guide us to the cost – effective.

کلیدواژه ها:

Cholecystitis ، Positive prediction ، Detection ، Sensitivity