One-Pot Synthesis of Octahydroquinazolinone Derivatives Using NASA in Solvent-Free Condition

Nano alumina sulfuric acid (NASA) has been prepared and used as a recyclable catalyst for the Biginelli synthesis of some biologically active quinazolinones/thiones under solvent-free conditions. This method has advantages such as the avoidance of organic solvents, high yield of pure products, short reaction times, and operational simplicity

کلیدواژه ها:

Biginelli reaction ، Octahydroquinazolinone derivatives ، nano alumina sulfuric acid ، multi component reaction