Prevalence of HLA-E alleles (HLA-E*01:01 and HLA-E*01:03) in a healthy population of Iran

سال انتشار: 1394
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 374

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شناسه ملی سند علمی:

NCNCMB02_128

تاریخ نمایه سازی: 12 تیر 1395

چکیده مقاله:

HLA-E locus is a human major histocompatibility complex (MHC) gene which is highly conserved through evolution and has low polymorphism. HLA-E is playing immune modulation and immune suppression roles by interaction with specific receptors of T cells, natural killer cells and macrophages. The aim of this study was to survey the HLA-E polymorphism in a healthy population of Iran

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نویسندگان

Zahra Hatami

Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

Ahmad Zavaran Hosseini

Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

Fatemeh Yari

Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.

Mohammad Reza Deyhim

Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran