Synthesis, characterization and application of Fe(III) loaded on SBA-15 nanocatalist for preparation of heterocyles of benzoxazole, benzimidazole and benzothiazole in aqueous medium

Development of researches in nano technology caused outspread of nano in many context of the science andindustry include pharmacutical industry. Sinceabout 80% of processes in chemical industry depends on catalysts towork efficiently[1]. Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow forrapid and selective chemical transformations with the benefits of excellent product yield and of catalyst separationand recovery[2]. Mesoporous silica is a form of silica and a recent development in nanotechnology. The mostcommon types of mesoporous nanoparticles are MCM-41 and SBA-15 .Research continues on the particles whichhave applications in catalysis, imaging, drug delivery, biosensors, and many applications in medicines. [3].Accordingly, we prepareda mesoporessilica, SBA-15 [4،5],grafthing Fe(III), to produce a new nanoporous, schiffbase Fe(III)-SBA-15 for use in the synthesis of heterocycles of benzoxazole, benzimidazole and benzothiazole[5].Since they are bio logical active and widely used in pharmacutical industry having properties of antialzheimerdisease, antiviral and anticancer[6].

کلیدواژه ها:

Nanocatalyst ، Fe(III)-SBA ، Benzoxazoles ، Benzimidazoles ، Benzothiazoles