Sensitivity Analysis of Nano-contact Mechanics Models by using the EFAST sensitivity analysis method

The variance-based sensitivity analysis methods, nowadays, have found wide-ranging applications in variousscientific fields for modelling analysis. The Sobol and EFAST variance-based sensitivity analysis techniques haveattracted more attention due to their capabilities. Since the Sobol method has a lower computational efficiency relativeto the EFAST, in this paper, the EFAST method is used for the first time for the sensitivity analysis of the parameters of5 contact nanomechanics models in the AFM-based manipulation of biological cells in bio-environments. The aim of thiswork is to analysis and compare the sensitivities of theoretical and experimental contact models. In this analysis, theYoung’s modulus, adhesion energy, Poisson’s ratio and the particle radius have been considered as the effectiveparameters. The results indicate that the adhesion energy and the Young’s modulus are the sensitive parameters and thePoisson’s ratio and particle radius are the insensitive parameters

کلیدواژه ها:

sensitivity analysis ، contact nanomechanics ، EFAST method ، Young’s modulus ، adhesionenergy ، Poisson’s ratio ، particle radius