Fe3O4/SBA-15: Preparation, characterization and application as a magnetically recoverable nanocatalyst for the one-pot three-component synthesis of quinazolinone derivatives

An environmentally benign and clean magnetic silica-based composite nanoparticles (Fe3O4/SBA-15) as anheterogeneous nanocatalyst was prepared and its properties and morphology were characterized by Fourier transformsinfrared spectroscopy (FT-IR), ultraviolet-visible diffuse reflectance spectroscopy (DRS), scanning electron microscopy(SEM), X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and Brunauer–Emmett–Teller (BET) multilayernitrogen adsorption method. Then, its catalytic activity was investigated in an important organic reaction for the one-potmulticomponent synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives starting from isatoic anhydride, ammoniumacetate and various aldehydes under mild reaction conditions and easy work-up procedure in refluxing ethanol in goodto excellent yields. The Fe3O4/SBA-15 nanocatalyst can be recovered easily and reused without any significant loss ofthe catalytic activity.

کلیدواژه ها:

Magnetic nanocatalyst ، Multicomponent reaction ، Dihydroquinazolinone ، Isatoic anhydride ، Silica ، Greenchemistry