Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features
محل انتشار: فصلنامه آسیب شناسی ایران، دوره: 10، شماره: 1
سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 556
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شناسه ملی سند علمی:
JR_IJP-10-1_012
تاریخ نمایه سازی: 13 مرداد 1394
چکیده مقاله:
Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessness for2 years. The CECT revealed multiple focal enhancing lesions along inferior mediastinal pleural surface and along lateral pleural surface. A thoracotomy and tumor excision was done and MPNST was diagnosed on microscopy and immunohistochemistry. This case highlights that this unusual tumor may involve lung parenchyma. So this possibility should be kept in mind in patients with intrathoracic mass.
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نویسندگان
Sunita Singh
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Megha Ralli,
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Sonia Hasija
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Renuka Verma
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India