The effects of CaO/P2O5 molar ratio changes on Invitro bioactivity of nanopowder glass via sol-gel in SiO2-CaO-P2O5 system

The ability of attachment to the living tissue via the reach CaP layer in their interface is one of the most important properties of bioactive glasses. In recent years, there was attempt to improve the bioactivity of glasses, that in this way the effect of composition on some properties of these glasses is cosidrable. In this project molar ratio of CaO/P2O5 as a effective parameter on chemical composition is investigated. To this aim, a gel was formed with constant molar percentages for SiO2 (%60 Mole) and 3, 6, 9, 12 and 15 for CaO/P2O5 molar ratio. So 30, 34.3, 36, 36.9 and 37.5 for CaO and 10, 5.7, 4, 3.07 and 2.5 for P2O5 was calcuteted. The thermal treatments of gels were investigatetd with STA, finally gels formed and calcined at 600˚C to obtain glass powderswith different composition. For Invitro assay the powders were soaked in simulated body fluid (SBF) for 14 days. To investigate the bioactivity of the glasses, FT-IR before andafter & ICP after soaking in SBF was conducted. Finally, after finding the optimalcomposition, the morphology of the samples were studied with XRD. It was concluded that the sample with 60mol% SOi

کلیدواژه ها:

bioglass ، calcium phosphate ، hydroxyapatite ، simulated body fluid