Potential Effects of Minerals and Phytochemicals in Bajakah–Stevia Herbal Tea: Implications for Glycemic and Inflammatory Regulation

Chronic inflammation is a biological underpinning of metabolic disorders, including diabetes mellitus. This study was conducted to examine the potential effects of several minerals and phytochemicals in Bajakah (Spatholobus littoralis Hassk.) – Stevia (Stevia rebaudiana) herbal tea and their implications for the regulation of glycemic and inflammatory responses. Forty-two streptozotocin-induced diabetic rats were used in this experimental study and divided into six groups. Physicochemical and nutritional properties were evaluated using standard analytical methods, while mineral composition was quantitatively determined by inductively coupled plasma mass spectrometry (ICP-MS). Blood glucose and serum interleukin-۶ (IL-۶) were measured after ۲۱ days of treatment. This formulation presented a mineral-rich profile, particularly in potassium, magnesium, and calcium, with low soluble sugar content and moderate electrolyte content. Treatment reduced fasting blood glucose levels by approximately ۵۴.۲% (p < ۰.۰۰۱) and decreased IL-۶ levels by ۲۲.۸۱% (p < ۰.۰۰۱). These findings suggest that mineral components and phytochemicals may collectively contribute to glycemic and inflammatory regulation. This study highlights the potential role of mineral-associated bioactivity in herbal systems and supports the formulation's application as a functional bioactive beverage.

کلیدواژه ها:

Spatholobus littoralis Hassk ، Stevia rebaudiana ، Minerals ، Diabetes Mellitus ، Inflammation