Aerobic Interval training as non-pharmacological treatment in some coronary atherosclerosis indicators in inactive adult obese men

Accumulating evidence suggests that obesity is major risk factors for cardiovascular diseases and atherosclerosis and regular physical activity as a non-pharmacological treatment in obesity induced diseases. This study aimed to determine the effect of interval training on Interferon-γ (IFN-γ) and C Reactive Protein (CRP) as coronary atherosclerosis indicators in adult obese males. Methods: For this purpose, ۲۴ inactive adult obese males (۳۰≤BMI≤۳۶) were randomly divided into experimental (n=۱۲) and control (n=۱۲) groups. Then experimental subjects were participated in ۸ weeks interval training (۳ times/weekly) at %۵۰–۷۰ HRmax and subjects in control group continued inactive lifestyle. Fasting serum IFN-γ and CRP were measured before and ۴۸ hours after lasting exercise session. Anthropometrical indices were measured before and after exercise intervention of groups. Data were compared with independent and paired sample t student using computer with SPSS Version ۲۲.۰. A p-value less than ۰.۰۵ was considered statistically signigcant.Results: No significant difference were observed in all anthropometrical and clinical markers at baseline between groups (p>۰.۰۵). Aerobic interval training resulted in significant decrease in anthropometrical indices (p<۰.۰۵). Training intervention also led to significant decrease in serum IFN-γ (p=۰.۰۰۵) and CRP (p=۰.۰۰۱) in experimental group. All variables remained without change in control subjects (p<۰.۰۵).Conclusion: Based on our finding, it be concluded that aerobic interval training with be emphasis improvement in IFN-γ and CRP may be slow the onset of atherosclerosis in adult obese men.

کلیدواژه ها:

Obesity ، Interval training ، Atherosclerosis ، Pro-inflammatory cytokine