The effect of O۱۰plus supplementation during total resistance exercises on serum nitric oxide and H۲O۲ as vascular endothelial function in inactive overweight females

Introduction: Obesity and overweight is associated with metabolic disorders such as type ۲ diabetes and vascular endothelial dysfunction. This study aimed to assess the effect of Q۱۰plus ingestion during total resistance exercises (TRX) training on nitric oxide (NO) and hydrogen peroxide (H۲O۲) as vascular endothelial function in inactive overweight females. Methods: In this semi-experimental study, ۴۸ adult overweight females aged ۳۰-۴۰ years were randomly divided into control (no intervention); exercise (TRX training, ۸ weeks), supplement (Q۱۰plus, ۸ weeks, ۱۰۰ mg/daily) and combined group (TRX+ Q۱۰plus). Anthropometrical indices and fasting serum NO and H۲O۲ concentration were measured before and ۴۸ after lasting exercise session and compared by ANCOVA with Bonferroni post hoc test between groups. Results: Serum NO significantly increased in exercise (p=۰.۰۰۱), supplement (p=۰.۰۲۶) and combination (p=۰.۰۰۱) groups. In addition, H۲O۲ significantly decreased by exercise and combination groups compared to control group (p=۰.۰۲۸, p=۰.۰۱۹ respectively). No significant difference were observed between other groups (p > ۰.۰۵).Conclusion: Based on these findings, although TRX and Q۱۰Plus consumption are each independently associated with improved vascular endothelial function, their simultaneous implementation is not more effective than either of them alone.

کلیدواژه ها:

Q۱۰plus ، TRX training ، Vascular function ، Overweight ، Nitric oxide