Effect of white noise on physiological parameters and pain levels during airway suctioning in preterm infants admitted to a neonatal intensive care unit: A Randomized Clinical Trial

Background: Preterm neonates are frequently exposed to painful procedures in neonatal intensive care units (NICUs), including endotracheal suctioning. Non-pharmacological interventions such as white noise may help reduce pain and improve physiological stability. This study aimed to investigate the effect of white noise on pain intensity and physiological parameters in preterm neonates during airway suctioning. Methods: This parallel-group randomized controlled clinical trial was conducted on ۵۰ preterm neonates admitted to the NICU of Afzalipour Hospital, Kerman, Iran. Eligible neonates were randomly assigned to intervention and control groups using a random number table. Allocation concealment was ensured using sequentially numbered, opaque, sealed envelopes prepared by an independent researcher. Neonates in the intervention group were exposed to white noise at ۴۵ dB from ۵ minutes before until ۱۰ minutes after suctioning, whereas those in the control group received routine care. Pain was assessed using the Neonatal Infant Pain Scale (NIPS). Physiological parameters, including heart rate, oxygen saturation, respiratory rate, and body temperature, were recorded before, during, and after suctioning. Body temperature was measured using the skin temperature probe integrated into the neonatal vital signs monitor. Data were analyzed using SPSS v۲۳. Repeated-measures analysis of variance with Greenhouse-Geisser correction was used to evaluate changes over time between groups. Independent t-test, Chi-square test, and Fisher’s exact test were applied where appropriate. A P-value <۰.۰۵ was considered statistically significant. Results: The intervention group showed significantly lower pain scores (P=۰.۰۰۱), heart rate (P<۰.۰۰۱), and respiratory rate (P=۰.۰۱۰) during suctioning compared with the control group. Oxygen saturation levels were significantly higher in the intervention group during the procedure (P<۰.۰۰۱). No significant differences were observed in body temperature between groups (P=۱.۰۰۰). Conclusion: White noise reduced pain scores and improved heart rate, respiratory rate, and oxygen saturation during airway suctioning in preterm neonates. These findings support the use of white noise as a complementary non-pharmacological intervention in NICU care.

کلیدواژه ها:

Premature Infant ، Pain ، Suction ، Neonatal intensive care unit ، White Noise