Dietary supplementation with Adiantum capillus-veneris and Ferula gummosa enhanced antioxidant status and innate immune responses in Rainbow trout (Onchorhynchus mykiss)

This study investigated the effects of dietary supplementation with Adiantum capillus-veneris and Ferula gummosa and a mixture of them on antioxidant status and innate immune responses in rainbow trout (Oncorhynchus mykiss). Fish with initial weight of ۲۰.۲ ± ۰.۰۱ g were fed experimental diets containing plant powders individually and in combination for ۸ weeks. Results indicated significant improvements in antioxidant enzyme activities including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), No significant difference was seen in malondialdehyde (MDA) levels in treatments (p > ۰.۰۵). Innate immune indices namely lysozyme activity, complement activity (ACH۵۰), as well as serum immunoglobulin M (IgM) were significantly enhanced, particularly in the combined treatment group (p ˂ ۰.۰۵). Administration a mixture of ۰.۵% A. capillus-veneris and ۰.۵% F. gummosa showed a synergistic effect between antioxidant-rich and immunostimulatory phytochemicals, highlighting their potential as natural alternatives to antibiotics in aquaculture.

کلیدواژه ها:

Adiantum capillus-veneris ، Antioxidative status ، Ferula Gummosa ، Immunity