Recent developments in the applications of synthetic polymers in osteogenesis: A review

AbstractAccording to ۲۰۲۱ Global Burden of Disease (GBD) statistics, approximately ۱۷۲.۷۹ million cases of bone fractures were reported. This global challenge underscores the importance of treatment and the improvement of human quality of life. Tissue engineering and advancements in synthetic polymers are contributing to the repair of bone fractures. This review examines the role of synthetic polymers, such as poly(lactic acid), poly(lactic-co-glycolic acid), and polycaprolactone(PCL), in various stages of bone tissue engineering, their unique characteristics, and the applications of these materials in this field. This study also compares the advantages and disadvantages of synthetic polymer scaffolds and their function in hybrid scaffolds. The use of bioactive agents and hybrids with natural polymers contributes to the advancement of tissue engineering in the osteogenesis process.

کلیدواژه ها:

hybrid scaffolds ، Bone tissue engineering ، Synthetic polymers ، bioactive agent