The Relation between Serum Magnesium Level and Severity of Hypertension

Background: Hypertension is a significant global health problem that is mainly related to cardiovascular diseases and cerebrovascular complications. Variations in the levels of risk factors for this condition, such as a diet high in salt and low in potassium, obesity, consumption of alcohol, lack of activity, and poor lifestyle habits, might be responsible fora portion of the regional heterogeneity in the prevalence of hypertension. This study assessed the relation between serum magnesium level and the severity of hypertension.Methods: In a cross sectional study from ۲nd October ۲۰۲۴ to the end of December ۲۰۲۴, ۱۵۰ patients with hypertension from Al-Hakim General Hospital were enrolled. The number of antihypertensive drugs used for the treatment was considered as a marker for severity of hypertension. All participants underwent evaluation for coronary artery disease and stroke. The xylidyl blue method (magnesium liquicolor-human kit) was used to assess the level of serum magnesium in sera of the patients.Results: Patients who needed a multiple antihypertensive medication had lower serum magnesium level and demonstrated a significant inverse relationship between serum magnesium level and the number of antihypertensive medications taken. Patients with managed and uncontrolled hypertension exhibited a significant difference in serummagnesium concentration, with those with uncontrolled blood pressure having a lower magnesium level. Serum magnesium level was significantly lower in obese patients than in normal-weight and overweight persons.Conclusion: Hypertensive patients who needed multiple antihypertensive drugs showed a significantly lower serum magnesium level.

کلیدواژه ها:

Hypertension ، magnesium ، Antihypertensive ، Cardiovascular diseases ، Iraq