Surveillance of Infectious Agents in Acute Febrile Illnesses in a Tertiary Care Hospital in Northern India

Background: Acute febrile illnesses (AFIs) are a major cause of morbidity in India, particularly during the monsoon season, posing significant diagnostic challenges due to overlapping clinical features. This study aimed to investigate the main AFI causes in northern India. Materials & Methods:This prospective observational study was conducted at a tertiary care hospital in northern India from July ۲۰۲۳ to December ۲۰۲۴ to determine the aetiological spectrum of AFIs. A total of ۸۱۲۷ patients were evaluated using rapid diagnostic tests and standard microbiological methods for dengue, typhoid, hepatitis A and E, chikungunya, scrub typhus, and malaria. Findings: Dengue and typhoid were the most frequently identified AFI causes, followed by viral hepatitis and other vector-borne infections. Mixed infections were also observed, highlighting diagnostic complexity. Conclusion: The findings emphasize the importance of laboratorysupported surveillance to enable early outbreak detection, improve case management, and guide public health interventions in endemic regions.

کلیدواژه ها:

Acute febrile illness ، Dengue ، Typhoid ، Hepatitis A ، Hepatitis E ، Scrub typhus ، Surveillance