Antimicrobial Susceptibility of Bacillus Cereus Isolates from Different Infectious Sources

The study aimed to evaluate and compare the susceptibility of Bacillus cereus isolates to antimicrobials isolated from a variety of locations in Iraq. ۱۲۰ samples, consisting of ۲۰ clinical and ۱۰۰ food-derived samples. The samples were cultured on Nutrient Agar, Blood Agar and Polymyxin Pyruvate Egg Yolk Mannitol Bromothymol Blue Agar (PEMBA) medium, and the final confirmation of the B. cereus isolates were performed using the VITEK® ۲ system. representative clinical and food isolates were compared against a group of antimicrobials using the disk diffusion method according to the CLSI M۴۵ A۳ ۲۰۲۴ standards. The distribution of the inhibition zones. The food isolates had the greatest level of susceptibility to the antibiotics tested (۳۹.۸۳% susceptibility to carbapenems, followed by ۲۷.۱۲% susceptibility to fluoroquinolones). All the other antibiotics showed less than half the level of inhibition (glycopeptides ۱۱.۴۴%; aminoglycosides ۱۱.۰۲%; tetracyclines ۱۰.۵۹%). In contrast to the food derived strains, the clinical isolates showed lower levels of inhibition than found in all tested food derived strains (۳۲.۱۰% susceptibility to carbapenems and ۲۹.۶۳% to fluoroquinolones), with both aminoglycosides and tetracyclines having ۱۲.۹۶% respectively and glycopeptides ۱۲.۳۵%. Both the food derived and clinical strains exhibited ۱۰۰% level of intrinsic resistance (۰.۰%) to trimethoprim. The study provided data indicating there are substantial differences between the efficacy of several classes of antimicrobial agents against B. cereus.

کلیدواژه ها:

: Bacillus cereus ، Antimicrobial susceptibility ، VITEK ۲ ، Food borne