Review of Contributing Factors and Treatment Options for Non-Alcoholic Fatty Liver disease (NAFLD)

The aim of this study is to investigate the exacerbating factors of Non-Alcoholic Fatty Liver disease (NAFLD) and its treatment options. Small droplets of lipid in the liver without significant alcohol consumption are a hallmark of nonalcoholic fatty liver disease. Disease can advance from fat storage alone (steatosis) without inflammation to necroinflammation (steatohepatitis). Fast food habits are known to contribute to hepatic steatosis through several mechanisms, including insulin resistance. Following "western" eating habits greatly raised the risk of NAFLD. Controlling the body's mass, glycol-metabolism, and lipid metabolism is the cornerstone of treatment. Physical activity (PA) is one of the most important activities that guarantees balanced weight reduction and calorie restriction in the body. PA efficiently burns fat and reduces insulin resistance. A personality disorder (PD) was found to be substantially more common in NAFLD patients than in non-NAFLD individuals with liver disease. Obesity has also been connected to anxiety and depression, with emotional eating having a strong positive correlation with both. Depression may be more strongly associated with advanced stages of NAFLD. The incidence of NAFLD is increased by sleep deficiency and poor sleep. Poly Cystic Ovarian Syndrome (PCOS) and NAFLD may be significantly influenced by sex hormones, particularly elevated blood androgen levels. NAFLD has been linked to subclinical or obvious hypothyroidism. It has been found that steroid hormones are crucial for lipid metabolism. Men with NAFLD are linked to reduced serum testosterone levels, and Total Testosterone (TT) levels are positively associated with NAFLD in women.

کلیدواژه ها:

NAFLD ، eating habits ، physical activity ، hormones ، metabolism