Bridging the Divide: A Systematic Review of Telehealth's Impact on Healthcare Access for Individuals with Down Syndrome

Introduction: Down syndrome (DS) is the most common chromosomal disorder that causes slow mind. People that have DS find it hard to get good health care as they are often too far away, have trouble talking to people and often do not get good care. Today there are new ways of care with technology. But we do not know if this new way will work for people with DS. In this paper we look at how health care with technology can help people with DS get the health care they need. Search Strategy: A broad search of the papers was done through four online databases (PubMed, Scopus, Web of Science, and Google Scholar) from the start till May ۳۱, ۲۰۲۵. The search plan used MeSH terms and related keywords. The process of picking studies used a two-step process with Rayyan.ai, with three people looking at the titles, abstracts and the full text. Results: The search found ۴۰۶ articles that could be relevant; ۳۹ studies met the rules for being in the review. Most studies were from rich countries and had anywhere from ۳-۱۲۳,۰۲۴ people in them. The most common video call type was video call platforms, then mobile health apps. The main types of care were speech and language therapy, early help, and exercise programs. On average, tech worked well and people liked it. The results showed clear change: ۲۳% fewer visits to ER, more people saw special doctors (۶۷% to ۸۹%) and speech was clearer in ۷۶% of people. Conclusion and Discussion: This review shows strong proof that using the internet can help people with DS get better care and do better in their lives. It can help with talking, getting over pain and keeping safe. Future work should look at how well these tools work over time, see if they can be used in parts of the world where people have little money, and learn how to design help so that these tools can give more help to individuals with Down syndrome. These trials show that apps can be a life-long buddy for those old help ways.