The comparison of the diagnostic accuracy of lung perfusion scan between patients with and without chronic obstructive pulmonary disease

Introduction: Diagnostic accuracy of lung perfusion scan (LPS) for detection of pulmonary thromboembolism (PTE) is not well defined in patients with chronic obstructive pulmonary disease (COPD). In the current study, we intended to compare the scan performance between patients with and without COPD.Methods: Study comprised suspected PTE patients who had LPS in two group of patients with and without COPD. Scans were done employing SPECT imaging and interpreted using PISAPED positive/negative criteria considering chest CT comparison. The pulmonologist final decision on the presence or absence of PTE was collected at ۳-month follow up visit. This clinical decision was made based on the response to anticoagulation or therapies directed to other diagnoses, and consideration of all imaging and examinations available including calf ultrasonography, echocardiography, CT angiography, and the ۳-month delayed LPS. The accuracy of the LPSs between those with and without COPD was compared.Results: Fifty-two patients without COPD and ۴۹ patients with COPD were included. Out of all, ۲۸ had PTE comprising ۱۱ patients in COPD group (۲۱.۲%) and ۱۷ in non-COPD (۳۴.۷%). In ۳-month follow up, pulmonologist diagnosed ۲۸ patients had PTE which exactly matched the initial report of LPS. The accuracy of the scan was ۱۰۰% similarly in patients with and without COPD.Conclusion: The results support the optimal diagnostic performance of LPS for PTE similarly in patients with and without COPD.

کلیدواژه ها:

Pulmonary thromboembolism ، Lung perfusion scan ، Chronic obstructive pulmonary disease