<span lang="EN-GB">The Relationship between Anthropometric Indices and Lipid Profile in PCOS Women: A Cross-sectional study

Background & aim: Infertility presents a formidable challenge to global public health, with polycystic ovary syndrome (PCOS) emerging as a prominent contributor. PCOS is associated with persistent health complications, such as metabolic syndrome, type ۲ diabetes, and cardiovascular diseases. Elevated body weight and central adiposity exacerbate the likelihood of anovulation and infertility in women. This study examined the relationship between anthropometric measurements and lipid profiles among infertile women with PCOS.Methods: This cross-sectional study was conducted at an infertility treatment center in Mashhad, Iran, between May ۲۰۲۳ and January ۲۰۲۴. The study enrolled ۲۸۰ married women aged ۱۸–۴۵ years who met inclusion criteria, specifically those diagnosed with both PCOS and infertility. Participants were selected through consecutive sampling and their anthropometric measurements were assessed by trained personnel. Participants' lipid profile, were assessed following a ۱۴-hour fasting period. Statistical analysis was performed with SPSS using Pearson correlation and ANOVA tests.Results: A significant positive correlation was found between normal Body Mass Index and triglyceride levels (P=۰.۰۳۰). Likewise, individuals with a BMI exceeding ۳۰ displayed a positive correlation with elevated TG levels (P=۰.۰۳۵). Furthermore, a statistically significant positive correlation was observed between Waist-to-Height Ratio (WHtR) values exceeding ۰.۵۷ and elevated TG levels (P=۰.۰۰۳).Conclusion: PCOS women, characterized by diverse features, exhibited distinct lipid profiles. The intricate relationship observed between lipid metabolism and various PCOS traits may shed light on the heightened susceptibility to long-term complications associated with elevated lipid levels. Regular monitoring of blood lipids and management of central obesity are imperative for women with PCOS.

کلیدواژه ها:

Polycystic ovary syndrome ، Anthropometric ، Dyslipidemia