ورود
مقالات فارسیISIکنفرانسهاژورنالها

Smart micro/nanoneedles for gene delivery

محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 29، شماره: 7
سال انتشار: 1405
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 97

فایل این مقاله در 21 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/2643983

شناسه ملی سند علمی:

JR_IJBMS-29-7_002

تاریخ نمایه سازی: 1 تیر 1405

چکیده مقاله:

Gene therapy, a transformative field in biomedicine, holds immense promise for treating a wide range of diseases. Smart micro/nanoneedles (MNs/NNs) emerged as non-viral carriers, offering safety and reduced immunogenicity, in addition to precise and controlled gene delivery, and represent promising platforms for gene delivery. They can also be tailored to respond to specific biological or environmental triggers, enabling precise targeting and localized delivery, ensuring that therapeutic genes reach their intended destination. Despite significant progress, challenges persist in scalable manufacturing, biocompatibility and safety, and genetic cargo stability. The incorporation of artificial intelligence (AI) into design and predictive modelling offers promising and cost-effective solutions to these limitations. This review provides a comprehensive analysis of MN/NN fabrication methodologies that enable structural and functional customization, while highlighting the interdisciplinary nature of MN/NN technologies and their transformative role in the future of gene therapy.

کلیدواژه ها:

Biomedicine ، Carrier ، Gene delivery ، Microneedle ، Nanoneedle

نویسندگان

Majid Farhadi

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

Gelareh Karimi

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

Zahra Salmasi

Departments of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Somayeh Marouzia

Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Mosaffa

Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Maryam Hashemi

Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Qie B, Tuo J, Chen F, Ding H, Lyu L. ...
  • Henderson ML, Zieba JK, Li X, Campbell DB, Williams MR, ...
  • Shahgordi S, Oroojalian F, Hashemi E, Hashemi M. Recent advances ...
  • Abas MDM, Asri MFM, Yusafawi NAS, Rosman NAZ, Baharudin NAZ, ...
  • Belete TM. The current status of gene therapy for the ...
  • Azimifar MA, Hashemi M, Babaei N, Salmasi Z, Doosti A. ...
  • Singh D, Singh S, Tandon N, Thakur A, Bedi N. ...
  • Temin HM. Mixed infection with two types of Rous sarcoma ...
  • Blaese RM, Culver KW, Miller AD, Carter CS, Fleisher T, ...
  • Wirth T PN, Ylä-Herttuala S. History of gene therapy. Gene ...
  • McManus MT, Sharp PA. Gene silencing in mammals by small ...
  • Alhasso B, Shareef A, Baldaniya L, Oweis R, Jyothi SR, ...
  • Miller JC, Holmes MC, Wang J, Guschin DY, Lee Y-L, ...
  • Chen X. Current and future technological advances in transdermal gene ...
  • Escoffre J-M, Teissié J, Rols M-P. Gene transfer: How can ...
  • Sabatino DE, Bushman FD, Chandler RJ, Crystal RG, Davidson BL, ...
  • Barquinero J, Eixarch H, Perez-Melgosa M. Retroviral vectors: New applications ...
  • Cockrell AS, Kafri T. Gene delivery by lentivirus vectors. Mol ...
  • Robbins PD, Ghivizzani SC. Viral vectors for gene therapy. Pharmacol ...
  • Salmasi Z, Hashemi M, Mahdipour E, Nourani H, Abnous K, ...
  • Salmasi Z, Mokhtarzadeh A, Hashemi M, Ebrahimian M, Farzad SA, ...
  • Cole G, Ali AA, McCrudden CM, McBride JW, McCaffrey J, ...
  • Ramamoorth M, Narvekar A. Non viral vectors in gene therapy-an ...
  • Wells JM, Li LH, Sen A, Jahreis GP, Hui SW. ...
  • Stein U, Walther W, Stege A, Kaszubiak A, Fichtner I, ...
  • Lin MT, Wang F, Uitto J, Yoon K. Differential expression ...
  • Pamornpathomkul B, Wongkajornsilp A, Laiwattanapaisal W, Rojanarata T, Opanasopit P, ...
  • Mehier-Humbert S, Guy RH. Physical methods for gene transfer: Improving ...
  • Hu Y, Xu B, Xu J, Shou D, Liu E, ...
  • Shin CI, Jeong SD, Rejinold NS, Kim Y-C. Microneedles for ...
  • Phoka T, Thanuthanakhun N, Visitchanakun P, Dueanphen N, Wanichwecharungruang N, ...
  • Saeedi M, Morteza-Semnani K, Akbari J, Hajheydari Z, Goodarzi A, ...
  • Chabri F, Bouris K, Jones T, Barrow D, Hann A, ...
  • Henry S, McAllister DV, Allen MG, Prausnitz MR. Microfabricated microneedles: ...
  • Donnelly RF, Moffatt K, Alkilani AZ, Vicente-Pérez EM, Barry J, ...
  • Kaushik S, Hord AH, Denson DD, McAllister DV, Smitra S, ...
  • Ali AA, McCrudden CM, McCaffrey J, McBride JW, Cole G, ...
  • DeMuth PC, Min Y, Huang B, Kramer JA, Miller AD, ...
  • Duong HTT, Yin Y, Thambi T, Nguyen TL, Phan VG, ...
  • Liu B, Yi X, Zheng Y, Yuan Z, Yang J, ...
  • Akbuğa FJ, Arpa MD, Şalva E. Nanoneedle-Based Transdermal Gene Delivery: ...
  • Bagde A, Dev S, Sriram LMK, Spencer SD, Kalvala A, ...
  • Duong HTT, Kim NW, Thambi T, Phan VG, Lee MS, ...
  • Xu Q, Li X, Zhang P, Wang Y. Rapidly dissolving ...
  • Yang HW, Ye L, Guo XD, Yang C, Compans RW, ...
  • Kim M, Jung B, Park J-H. Hydrogel swelling as a ...
  • Xu C, Wu F, Duan Z, Rajbanshi B, Qi Y, ...
  • Liu G, Deng Y, Song Y, Sui Y, Cen J, ...
  • Deng Y, Chen J, Zhao Y, Yan X, Zhang L, ...
  • Chong RHE, Gonzalez-Gonzalez E, Lara MF, Speaker TJ, Contag CH, ...
  • Seong H, Higgins SG, Penders J, Armstrong JPK, Crowder SW, ...
  • He G, Chen H-J, Liu D, Feng Y, Yang C, ...
  • Chiappini C, De Rosa E, Martinez JO, Liu X, Steele ...
  • Luo X, Yang L, Cui Y. Microneedles: Materials, fabrication, and ...
  • Saurer EM, Flessner RM, Sullivan SP, Prausnitz MR, Lynn DM. ...
  • Lutton REM, Larrañeta E, Kearney M-C, Boyd P, Woolfson AD, ...
  • Han D, Morde R, Mariani S, La Mattina A, Vignali ...
  • Vander Straeten A, Sarmadi M, Daristotle JL, Kanelli M, Tostanoski ...
  • Lee K, Kim JD, Lee CY, Her S, Jung H. ...
  • Li Y, Zhang H, Yang R, Laffitte Y, Schmill U, ...
  • Mikszta JA, Alarcon JB, Brittingham JM, Sutter DE, Pettis RJ, ...
  • Rezapour Sarabi M, Alseed MM, Karagoz AA, Tasoglu S. Machine ...
  • Jin Q, Chen HJ, Li X, Huang X, Wu Q, ...
  • Pearton M, Saller V, Coulman SA, Gateley C, Anstey AV, ...
  • Kim Y-C, Song J-M, Lipatov AS, Choi S-O, Lee JW, ...
  • Raju L, Hiremath SS. A state-of-the-art review on micro electro-discharge ...
  • García-López E, Siller HR, Rodríguez CA. Study of the fabrication ...
  • Azizi Machekposhti S, Khanna S, Shukla S, Narayan R. Microneedle ...
  • DeMuth PC, Su X, Samuel RE, Hammond PT, Irvine DJ. ...
  • Li X, Xu Q, Wang J, Zhang P, Wang Y, ...
  • Gonzalez-Gonzalez E, Speaker TJ, Hickerson RP, Spitler R, Flores MA, ...
  • Biswas A, Bayer IS, Biris AS, Wang T, Dervishi E, ...
  • Golshadi M, Wright LK, Dickerson IM, Schrlau MG. High-Efficiency Gene ...
  • Wang Y, Yang Y, Yan L, Kwok SY, Li W, ...
  • Cole G, McCaffrey J, Ali AA, McBride JW, McCrudden CM, ...
  • Koh KJ, Liu Y, Lim SH, Loh XJ, Kang L, ...
  • Noh I, Lee K, Rhee YS. Microneedle systems for delivering ...
  • Tang T, Deng Y, Chen J, Zhao Y, Yue R, ...
  • Li X, Xu Q, Zhang P, Zhao X, Wang Y. ...
  • Makvandi P, Jamaledin R, Chen G, Baghbantaraghdari Z, Zare EN, ...
  • Liu X, Song H, Sun T, Wang H. Responsive Microneedles ...
  • Karimi M, Ghasemi A, Zangabad PS, Rahighi R, Basri SMM, ...
  • van den Berg JH, Oosterhuis K, Hennink WE, Storm G, ...
  • Pearton M, Allender C, Brain K, Anstey A, Gateley C, ...
  • Yin Y, Su W, Zhang J, Huang W, Li X, ...
  • Wei Z, Zheng S, Wang R, Bu X, Ma H, ...
  • Hisazumi J, Kobayashi N, Nishikawa M, Takakura Y. Significant role ...
  • Wang M, Han Y, Yu X, Liang L, Chang H, ...
  • Piotrowski-Daspit AS, Kauffman AC, Bracaglia LG, Saltzman WM. Polymeric vehicles ...
  • Blömer U, Naldini L, Verma IM, Trono D, Gage FH. ...
  • Shi H, Xue T, Yang Y, Jiang C, Huang S, ...
  • Dinh L, Mahon L, Yan B. Nano-encapsulation and conjugation applied ...
  • Liang X, Zhang J, Ou H, Chen J, Mitragotri S, ...
  • Pan J, Ruan W, Qin M, Long Y, Wan T, ...
  • Gong D, Ben-Akiva E, Singh A, Yamagata H, Est-Witte S, ...
  • Kumar A, Wonganan P, Sandoval MA, Li X, Zhu S, ...
  • Ingrole RSJ, Gill HS. Microneedle coating methods: A review with ...
  • Briffault E, Garcia-Garcia P, Martinez-Borrajo R, Evora C, Delgado A, ...
  • Chen W, Li H, Shi D, Liu Z, Yuan W. ...
  • Zhang X, Zhou C, Chen T, Jiang Z, Lu C, ...
  • Makvandi P, Kirkby M, Hutton AR, Shabani M, Yiu CK, ...
  • Sun Y, Miao D, Zeng Z, Li X, Pu Y, ...
  • Han S, Wan H, Lin D, Guo S, Dong H, ...
  • He W, Kong S, Lin R, Xie Y, Zheng S, ...
  • Chumpu R, Chu C-L, Treeratanaphitak T, Marukatat S, Hsu S-H. ...
  • Chiappini C, Campagnolo P, Almeida CS, Abbassi-Ghadi N, Chow LW, ...
  • Sun Z, Hou Y. Intelligent micro/nanorobots for improved tumor therapy. ...
  • Shah SA, Oakes RS, Kapnick SM, Jewell CM. Mapping the ...
  • Zhang XP, He YT, Li WX, Chen BZ, Zhang CY, ...
  • Choi H-J, Yoo D-G, Bondy BJ, Quan F-S, Compans RW, ...
  • McCaffrey J, McCrudden CM, Ali AA, Massey AS, McBride JW, ...
  • Cary JH, Li BS, Maibach HI. Dermatotoxicology of microneedles (MNs) ...
  • Tarbox TN, Watts AB, Cui Z, Williams III RO. An ...
  • Moawad F, Pouliot R, Brambilla D. Dissolving microneedles in transdermal ...
    • نمایش کامل مراجع