Health benefits of Rosa damascena: scientific evaluation of its anti-inflammatory and antioxidant properties

Rosa damascena, known as Damask Rose, belongs to the family of Rosaceae and grows in Northern Asia and the mountains of Central Europe . For several centuries, this plant has been used as an advantageous and effective treatment for a wide range of diseases and in folk medicine for treating many diseases such as anti-inflammatory treatments , menstrual bleeding, digestive problems , strengthening the heart and chest , and abdominal pain. Anti-inflammatory effects of R. damascena and its constituents were shown in different inflammatory disorders by reducing white blood cell, neutrophil, eosinophil, and serum levels of inflammatory mediators such as phospholipase A۲ and total protein. This important ornamental plant has long been applied for industrial, physiological, and medicinal purposes . The physiological functions of Damask Rose may be somewhat related to the abundance of anthocyanidins and flavonoids. The plant and its constituents showed antioxidant effects by reducing malondialdehyde and nitric oxide levels but increased thiol, superoxide dismutase, and catalase levels in disorders associated with oxidative stress. Therefore anti-inflammatory, antioxidant, and immunomodulatory effects of R. damascena and its constituents, indicate a potential therapeutic effect of the plant and its constituent for treating inflammatory, oxidative, and immune dysregulation disorders.Rosa damascena, known as Damask Rose, belongs to the family of Rosaceae and grows in Northern Asia and the mountains of Central Europe . For several centuries, this plant has been used as an advantageous and effective treatment for a wide range of diseases and in folk medicine for treating many diseases such as anti-inflammatory treatments , menstrual bleeding, digestive problems , strengthening the heart and chest , and abdominal pain. Anti-inflammatory effects of R. damascena and its constituents were shown in different inflammatory disorders by reducing white blood cell, neutrophil, eosinophil, and serum levels of inflammatory mediators such as phospholipase A۲ and total protein. This important ornamental plant has long been applied for industrial, physiological, and medicinal purposes . The physiological functions of Damask Rose may be somewhat related to the abundance of anthocyanidins and flavonoids. The plant and its constituents showed antioxidant effects by reducing malondialdehyde and nitric oxide levels but increased thiol, superoxide dismutase, and catalase levels in disorders associated with oxidative stress. Therefore anti-inflammatory, antioxidant, and immunomodulatory effects of R. damascena and its constituents, indicate a potential therapeutic effect of the plant and its constituent for treating inflammatory, oxidative, and immune dysregulation disorders.

کلیدواژه ها:

Rosa damascena (Damask rose) ، Antioxidant activity ، Oxidative stress