A Case Report of Aplasia Cutis Congenita in Northeastern Iran

Aplasia Cutis Congenita (ACC) is a rare and astonishing congenital disorder characterized by localized or widespread absence of skin, particularly in the head region. ACC has an estimated incidence of ۰.۵ to ۱ in every ۱۰,۰۰۰ newborns. This disorder can damage various depths of the skin and, in some cases, is associated with bone abnormalities and cranial defects. While the exact pathophysiology of this disease is not yet fully understood, genetic factors, intrauterine infections, and vascular insufficiency have been proposed as its potential causes. In a specific case, a baby girl was born with a lesion measuring ۳ × ۳ centimeters in the anterior fontanel area, and brain ultrasound confirmed the diagnosis of Aplasia Cutis, so the infant was transferred to the intensive care unit. Treatment included regular dressing changes and antibiotic administration, and fortunately, the infant health improved after a few days and was discharged. The prognosis for small lesions is usually positive, but this disorder can lead to complications such as infection and bleeding. Given the possible connection between placental type and the occurrence of Aplasia Cutis, further research in this area is essential to gain a deeper understanding of the factors influencing this disorder and to improve treatment methods.

کلیدواژه ها:

Aplasia Cutis Congenita ، pathophysiology ، skin. ، آپلازی کوتیس مادرزادی ، پاتوفیزیولوژی ، پوست.