Background: Intracranial tumors in cats, although less common than in dogs, are of serious clinical concern due to their aggressive behaviour and critical location within the central nervous system. Intracranial brain tumors in cats, including intraventricular tumors, are most commonly diagnosed in middle-aged to older animals, typically between ۸ and over ۹ years of age. This report describes two cases of Domestic Shorthair cats, aged ۲ and ۱۱ years, referred to the Small Animal Teaching Hospital, University of Tehran, presenting with various neurological signs including seizures, convergent strabismus, setting sun sign, unilateral paralysis, and decreased level of consciousness (LOC). Clinical and historical findings suggested a central origin of the lesions. Methods: Computed tomography (CT) of the skull was performed in ۲ phases (plain and contrast-enhanced). In the ۲-year-old cat, imaging showed marked enlargement of the left retropharyngeal lymph node and an irregular intraventricular mass in the third ventricle, leading to obstructive hydrocephalus with severe ventricular dilation. In the ۱۱-year-old cat, a hyperattenuating lesion was observed within the third ventricle extending to the fourth ventricle, causing caudal displacement of the cerebellum and perilesional edema. Results: Based on imaging features, differential diagnoses included choroid plexus tumor (CPT), ependymoma, and intraventricular meningioma. CPTs typically display strong, homogeneous contrast enhancement and marked hydrocephalus, while ependymomas often show heterogeneous enhancement and extend along the CSF pathway. Intraventricular meningiomas, though rare, are seen as well-defined, smoothly margined masses with homogeneous enhancement. Conclusion: Contrast-enhanced CT is very helpful for identifying intraventricular tumors in cats. Although some radiologic features are similar, MRI is still needed for a definite diagnosis.These cases highlight the diagnostic value of CT in feline brain disorders. Combined therapeutic approaches, including ventriculoperitoneal shunting (VPS), surgical excision, and radiotherapy, can improve clinical outcomes and prognosis in affected cats. However, both cats were euthanized at the owners’ request before any treatment. These cases remind clinicians to consider brain tumors in cats with neurological symptoms, even when rare.