Non-Effusive Feline Infectious Peritonitis in a Scottish Blue Cat: Case Report

Background: Feline infectious peritonitis (FIP) is a fatal, immune-mediated disease in cats caused by a virulent variant of feline coronavirus (FIPV). While most infections remain mild, spontaneous mutations can lead to systemic spread via monocytes and macrophages. FIP manifests in effusive (wet) and non-effusive (dry) forms, with the latter characterized by granulomatous lesions in abdominal and other organs. Diagnosis is challenging, but molecular techniques such as RT-PCR and immunocytochemistry improve detection. Methods: A ۵-year-old spayed Scottish Blue cat presented with diarrhea, vomiting, and fever. Clinical examinations were performed, and RT-PCR testing was conducted to diagnose feline coronavirus (FCoV) infection and confirm feline infectious peritonitis (FIP). Supportive care and antiviral therapy with remdesivir were initiated. Due to the owner’s financial constraints, the cat was euthanized. Results: A partial improvement of about ۸۰% was observed with remdesivir treatment. FCoV infection was confirmed by RT-PCR. Necropsy revealed mesenteric lymphadenomegaly with purulent necrosis and renal granulomas. Findings align with previously reported features of adult-onset dry FIP in purebred cats. Conclusion: This case highlights the diagnostic and pathological characteristics of adult-onset non-effusive FIP in a purebred cat, emphasizing the importance of molecular testing and necropsy for accurate diagnosis and understanding of disease progression.

کلیدواژه ها:

Feline infectious peritonitis ، Dry form ، PCR ، Cat