Assessment of Dosimetric Accuracy and Plan Quality in Prostate SBRT Using RapidArc with Analysis of Varian MLC Parameters

سال انتشار: 1404
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 22

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_IJMP-22-5_001

تاریخ نمایه سازی: 7 دی 1404

چکیده مقاله:

Introduction: Prostate cancer is a highly prevalent malignancy worldwide. Advances in radiotherapy, particularly SBRT, have enabled ultra-hypofractionated treatments that improve tumor control while reducing treatment time. This study evaluates the dosimetric accuracy and plan quality of prostate SBRT delivered using RapidArc technology on a Varian Millennium Multi Leaf Collimator (MLC) system.Material and Methods: Twenty-four patients with localized prostate adenocarcinoma received SBRT with a prescribed dose of ۳۶.۲۵ Gy in five fractions. Treatment planning was performed using Eclipse v۱۵.۶ with the Acuros XB algorithm, employing three ۶ MV Flattening Filter Free (FFF) arcs. Planning Target Volume (PTV) coverage, Organs At Risk (OAR) doses, Paddick Conformity Index (PCI), Gradient Index (GI), and Monitor Units (MU) were analyzed. MLC performance was assessed using trajectory log files to evaluate leaf speed and positional accuracy. Pre-treatment Quality Assurance (QA) was conducted using Electronic Portal Imaging Device (EPID)-based gamma analysis.Results: The mean PTV D۹۵ was ۳۵.۸۰ ± ۰.۴۶ Gy, with Dmax and Dmean of ۳۹.۸۰ ± ۱.۰۵ Gy and ۳۷.۱۰ ± ۰.۴۰ Gy, respectively. V۹۵% averaged ۹۹.۱۳ ± ۱.۱۴%, confirming adequate coverage. The bladder and rectum Dmax slightly exceeded constraints, while all other OAR objectives were met. Gamma pass rates exceeded ۹۹.۶% for the ۲%/۲mm criterion. MLC leaf speed remained below ۲.۵ cm/s, ensuring delivery accuracy.Conclusion: RapidArc-based prostate SBRT demonstrated high conformity, efficient delivery, and acceptable OAR sparing. Intra-fraction CBCT improved setup accuracy, and MLC log-file analysis confirmed mechanical precision, supporting the feasibility of this approach for localized prostate cancer.

کلیدواژه ها:

Prostatic Neoplasms Radiotherapy Intensity ، Modulated Radiotherapy Dosage Delivery of Health Care

نویسندگان

Ajithkumar M

Department of Radiotherapy, Meherbai Tata Memorial Hospital, Jamshedpur

Subhankar Show

Department of Radiotherapy, Meherbai Tata Memorial Hospital, Jamshedpur

Aaditya Prakash

Department of Radiotherapy,Tata MainHospital, Jamshedpur

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Dearnaley D, Syndikus I, Mossop H, Khoo V, Birtle A, ...
  • Freeman DE, King CR. Stereotactic body radiotherapy for low-risk prostate ...
  • Wieslander E, Jóhannesson V, Nilsson P, Kjellén E, Gunnlaugsson A. ...
  • van As N, Griffin C, Tree A, Patel J, Ostler ...
  • McDermott LN, Wendling M, van Asselen B, Stroom J, Sonke ...
  • Kjaer-Kristoffersen F, Ohlhues L, Medin J, Korreman S. RapidArc volumetric ...
  • Yoo S, Wu QJ, Lee WR, Yin FF. Radiotherapy treatment ...
  • Rana S, Rogers K, Lee T, Reed D, Biggs C. ...
  • Rana S, Rogers K, Pokharel S, Cheng C. Evaluation of ...
  • Huang K, Palma DA, Scott D, McGregor D, Gaede S, ...
  • Jolly D, Alahakone D, Meyer J. A RapidArc planning strategy ...
  • Paddick I. A simple scoring ratio to index the conformity ...
  • Wilke L, Andratschke N, Blanck O, Brunner TB, Combs SE, ...
  • Chen J, Cui W, Fu Q, Zhang H, Huang X, ...
  • Lin X, Sun T, Liu X, Zhang G, Yin Y. ...
  • نمایش کامل مراجع