CFD Analysis of Hemodynamic Changes in Aortic Coarctation: Investigating Pressure Gradient and Stenosis Severity

Aortic coarctation is a congenital narrowing of the aorta, typically occurring distal to the left subclavian artery, which leads to complications such as hypertension and impaired blood flow. Accurate diagnosis and assessment of this condition often rely on evaluating the pressure gradient between the regions proximal and distal to the coarctation. In this study, an idealized aortic geometry was utilized to simulate four cases of coarctation with varying degrees of stenosis, characterized by differences in diameter and length. Computational fluid dynamics (CFD) methods were employed to analyze the hemodynamic parameters, including pressure and velocity distributions. The simulations provided detailed insights into the flow behavior within the narrowed segments, revealing the impact of stenosis severity on key hemodynamic indicators. By examining pressure and velocity contours alongside the HOLMES parameter, a quantitative relationship between the pressure gradient and stenosis characteristics was established. The findings of this study underscore the importance of CFD as a non-invasive tool for understanding the hemodynamic alterations caused by aortic coarctation, contributing to improved diagnostic and treatment strategies. This research offers a foundation for further exploration of patient-specific models and real-world clinical applications.

کلیدواژه ها:

Aortic coarctation ، CFD ، hemodynamic parameters ، HOLMES