Phytochemical Profiling of Methanolic Leaf Extracts of Vietnamese Murraya koenigii, a Highly Valued Traditional Medicine, using UHPLC‐Q‐TOF‐MS/MS

Murraya koenigii (L.) Spreng (curry tree) is a tropical to subtropical tree originally from South Asia. The leaves of curry trees are an essential ingredient of Indian cuisine and are used as a flavoring in many dishes. The leaves are also widely used in Indian traditional medicine and possess the therapeutic potential due to the high content of biologically active compounds, including but not limited to flavonoids, steroids, alkaloids, phenolic compounds, etc. These compounds exhibit antioxidant, hypoglycemic, anticancer, antibacterial, and some other curative properties. It is well known that phytochemical composition is dependent on plant habitat. M. koenigii grows in Vietnam, where it is called “сà ri,” and is used in its cuisine. However, there is no data about the phytochemical profile of this plant from Vietnam. In this study, the extract of curry tree leaves was studied. For long-term methanol extraction, a maceration technique for ۷ days was used. The extract was analyzed by UV-spectroscopy and ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐fight tandem mass spectrometry (UHPLC‐Q‐TOF‐MS/MS). In the end, about two hundred matches with known substances including flavonoids, alkaloids, steroids, terpenoids, phenolic, and other compounds were identified in M. koenigii extract. In general, the phytochemical composition of Vietnamese M. koenigii resembles those of plants from other countries. However, several new compounds of unknown structure were found. Therefore, a furthermore detailed study of M. koenigii and other Murraya species native to Vietnam is needed.

کلیدواژه ها:

Curry tree ، Phytochemical composition ، Maceration ، Methanol extraction ، Mass-spectrometry