Strategies for Controlling Future Pandemics Similar to COVID-۱۹: A Systematic Review

Background: The COVID-۱۹ pandemic exposed both strengths and weaknesses in global health systems. This systematic review synthesizes global strategies used to control COVID-۱۹ and comparable pandemics to inform preparedness for future health crises. Methods: We systematically searched PubMed, Embase, Scopus, Web of Science, and Cochrane Library from ۲۰۱۹-۲۰۲۵. Eligible studies reported empirical evidence on non-pharmaceutical interventions (NPIs), vaccination, border control, surveillance, or governance. Data were extracted by two reviewers, and study quality was assessed using ROBINS-I and RoB۲ tools. Narrative synthesis and meta-analysis (where feasible) were performed. The review adhered to PRISMA ۲۰۲۰ guidelines. Results: Of ۵,۳۷۲ articles screened, ۱۴۲ met inclusion criteria. NPIs—particularly mask mandates, early lockdowns, and school closures-were consistently associated with reduced transmission and mortality. Vaccination campaigns substantially reduced severe disease and deaths, though their effect lagged NPIs by several weeks. Combined approaches were most effective. Governance and public trust were critical modifiers of success. Evidence gaps remain for low- and middle-income countries. Conclusion: Effective pandemic control requires early, layered interventions, rapid vaccine rollout, strong governance, and global equity in health resources. Policymakers should prioritize resilient health systems and international coordination. Keywords: Pandemic, COVID-۱۹, Public Health Strategies, Vaccination, Systematic Review

کلیدواژه ها:

Pandemic ، COVID-۱۹ ، Public Health Strategies ، Vaccination ، Systematic Review