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مقالات فارسیISIکنفرانسهاژورنالها

Optimize the Synthesis of Calcium Hydroxide/Levan/Silver Nanocomposite as an Antibacterial Agent

محل انتشار: نشریه متدهای شیمیایی، دوره: 10، شماره: 2
سال انتشار: 1405
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 98

فایل این مقاله در 14 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/2439771

شناسه ملی سند علمی:

JR_CHM-10-2_003

تاریخ نمایه سازی: 27 آبان 1404

چکیده مقاله:

Antimicrobial resistance (AMR) has become a worrisome problem due to the rapid increase in AMR phenotypes. This research aimed to investigate the antibacterial properties of calcium hydroxide/levan/silver nanocomposite against Enterococcus faecalis (E. faecalis) biofilm under in vitro conditions. In this study, nine experiments were designed to evaluate the antibacterial effects of synthesized nanocomposites against the oral pathogen E. faecalis using the Taguchi method. In these tests, three factors, which included calcium hydroxide nanoparticles, biopolymer levan and silver nanoparticles, were investigated at three different levels to determine the best ratio with the highest antibacterial activity. The nanocomposite synthesized under test condition ۵, including calcium hydroxide (۵۰ mg/mL), levan (۰.۵ mg/mL) and silver (۴ mg/mL), completely inhibited the growth of E. faecalis bacteria. Analysis showed that the nanocomposite and its components had a desirable structural and chemical composition, making it an effective antibacterial agent.

کلیدواژه ها:

Nanocomposite ، Calcium hydroxide ، Levan ، Silver ، Human Health

نویسندگان

Mohsen Safaei

Advanced Dental Science and Technology Research Center, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

Sabah Etemadi

Advanced Dental Science and Technology Research Center, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

Reza Hatam

Department of Endodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

Atefeh Khavid

Department of Oral and Maxillofacial Radiology, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

Atena Karimi

Department of Oral and Maxillofacial Radiology, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

Douglas Law

Faculty of Health and Life Sciences, INTI International University, Nilai ۷۱۸۰۰, Malaysia

Ling Shing Wong

Faculty of Health and Life Sciences, INTI International University, Nilai ۷۱۸۰۰, Malaysia

Mostafa Goodini

Department of Endodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

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