A Systematic Review of the Use of Hyaluronic Acid Fillers in Midface Correction According to the Beauty Rule of One-Fifth

Midface volume loss and contour irregularities significantly affect facial aesthetics and are commonly addressed in aesthetic medicine. The beauty rule of one-fifth, which divides the midface horizontally into five equal parts, serves as a foundational guideline for achieving balanced and harmonious facial proportions. This systematic review evaluates the current evidence on the use of hyaluronic acid (HA) fillers for midface correction based on the one-fifth beauty rule. A comprehensive literature search was conducted across multiple databases from ۲۰۱۰ to ۲۰۲۵. Included studies assessed HA filler applications targeting midfacial volumization and contouring with reference to the one-fifth guideline. Outcomes related to aesthetic improvement, patient satisfaction, procedural safety, and adherence to proportional principles were analyzed. The review demonstrates that HA fillers, when applied with respect to the one-fifth rule, yield significant enhancement in midface volume and contour harmony with high patient satisfaction and minimal adverse events. This approach offers a minimally invasive alternative to surgical interventions and underscores the importance of aesthetic proportionality in treatment planning. Future research should focus on standardized injection protocols aligned with anthropometric guidelines to optimize outcomes.

کلیدواژه ها:

hyaluronic acid fillers ، Midface Correction ، Beauty Rule ، One-Fifth