Introduction. Bariatric surgery (BS) is among the most effective treatments for severe obesity. However, it is essential to acknowledge the risk of serious short-term complications following the procedure. Case Presentation. We report four cases of Iranian patients admitted due to severe short-term complications following sleeve gastrectomy (SG), which included peritonitis, acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and sepsis. Based on their diagnoses and individual needs, two patients underwent exploratory laparotomy. All four cases were successfully treated with intravenous antibiotics, intensive supportive care, and continuous renal replacement therapy (CRRT) along with extracorporeal hemoperfusion. Conclusions. SG is one of the most commonly performed metabolic procedures worldwide. However, it can lead to severe, lifethreatening complications, such as
sepsis resulting from peritonitis and pneumonia. These cases underscore the importance of early recognition and effective treatment strategies for this patient population. A strict postoperative follow-up is essential for the early detection and management of complications, ultimately reducing morbidity and mortality rates.Introduction. Bariatric surgery (BS) is among the most effective treatments for severe obesity. However, it is essential to acknowledge the risk of serious short-term complications following the procedure. Case Presentation. We report four cases of Iranian patients admitted due to severe short-term complications following sleeve gastrectomy (SG), which included peritonitis, acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and sepsis. Based on their diagnoses and individual needs, two patients underwent exploratory laparotomy. All four cases were successfully treated with intravenous antibiotics, intensive supportive care, and continuous renal replacement therapy (CRRT) along with extracorporeal hemoperfusion. Conclusions. SG is one of the most commonly performed metabolic procedures worldwide. However, it can lead to severe, lifethreatening complications, such as
sepsis resulting from peritonitis and pneumonia. These cases underscore the importance of early recognition and effective treatment strategies for this patient population. A strict postoperative follow-up is essential for the early detection and management of complications, ultimately reducing morbidity and mortality rates.