Effect of resistance training with and without blood flow restriction on serum follistatin and leptin levels in active obese girls

Objective: Plasma follistatin and leptin proteins are important indicators in energy and metabolism regulation that also affect body weight. The aim of this study was to investigate the effect of resistance training with and without blood flow restriction on serum follistatin and leptin levels in inactive obese girls.Materials and Methods: Thirty inactive obese girls with an age range of ۲۰ to ۲۸ years participated in this study. The subjects were randomly divided into ۳ groups: resistance training with blood flow restriction and resistance training without blood flow restriction, and a control group (۱۰ subjects in each group). Data analysis was performed using paired t-tests and one-way ANOVA at a significance level of less than ۵%.Results: After ۱۲ weeks of participation in sports activity, follistatin levels in both resistance training groups with and without blood flow restriction increased significantly after training (p<۰.۰۵). On the other hand, leptin levels decreased significantly in these groups after training interventions (p<۰.۰۵). Regarding the main effect of groups, the results showed that there was a significant difference between the types of resistance training and the control group in follistatin (P=۰.۰۳۶) and leptin (P=۰.۰۱۵) levels.Conclusion: The findings indicate that resistance training can lead to an increase in plasma follistatin levels and a decrease in leptin in inactive obese girls. It is recommended that obese individuals use such resistance training with blood flow restriction as a non-invasive, low-cost, and side-effect-free method to promote health and lose weight

کلیدواژه ها:

resistance training ، follistatin ، Leptin ، blood flow restriction