Abnormal Chest Radiographic Findings According to Leukemia Subtype in Pediatric Patients with Leukemia

Introduction: Leukemia is the most common childhood malignancy, often associated with various thoracic complications. Chest radiography serves as an essential diagnostic tool for identifying respiratory manifestations and guiding clinical management in pediatric leukemia patients.Materials and Methods: This descriptive-analytical cross-sectional study evaluated ۵۶ pediatric leukemia patients hospitalized at Bouali Hospital in Ardabil, Iran, over a five-year period (۲۰۱۸–۲۰۲۳). Data regarding age, sex, leukemia subtype, respiratory symptoms, and chest X-ray findings were extracted from medical records and analyzed using SPSS version ۲۵.Results: Of the patients, ۸۳.۹% were diagnosed with acute lymphoblastic leukemia (ALL) and ۱۶.۱% with acute myeloid leukemia (AML). Abnormal chest radiographic findings were identified in ۶۲.۵% of patients, with pulmonary opacities (۲۳.۲%), peribronchial thickening (۱۴.۳%), pleural effusion (۱۴.۳%), and mediastinal mass (۸.۹%) being the most common. No statistically significant difference was found between leukemia subtypes regarding overall radiographic abnormalities (P > ۰.۰۵).Conclusion: Chest radiographic abnormalities are frequent in pediatric leukemia, regardless of subtype. Routine imaging is crucial for early detection of thoracic complications, even in asymptomatic cases.

کلیدواژه ها:

Pediatric Leukemia ، chest radiography ، Acute Lymphoblastic Leukemia ، Thoracic complications