Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa

Background: Carvacrol, a prominent phenolic compound found in Satureja and thyme, possesses a wide range of beneficial properties, including antibacterial, antifungal, anti-inflammatory, and anti-cancer activities. Objectives: This study aimed to determine the antibacterial effects of peptide-modified carvacrol on Staphylococcus epidermidis and Pseudomonas aeruginosa. Methods: Using disk diffusion and MIC methods, the antibacterial activity of peptide-modified carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa was evaluated. Results: The modified carvacrol demonstrated growth inhibition diameters of ۲۵mm and ۲۰mm against Staphylococcus epidermidis and Pseudomonas aeruginosa using the disk diffusion method. The minimum inhibitory concentration (MIC) against Staphylococcus epidermidis and Pseudomonas aeruginosa was ۱ g/ml and ۰.۵۱ g/ml, respectively. Conclusion: Peptide-modified carvacrol displays antibacterial effects.

کلیدواژه ها:

antibacterial ، Modified carvacrol ، Staphylococcus epidermidis ، Pseudomonas aeruginosa