Seroepidemiological prevalence of Helicobacter pylori in the south of Tehran, Iran

Background: Helicobacter pylori (HP) is one of the most prevalent infections globally, particularly in developing countries like Iran. The assessment of the disease in Tehran, the capital of Iran, is essential due to its high population density, inadequate sanitation infrastructure, and economic challenges.Objectives: This study aimed to evaluate the prevalence of anti-HP antibodies in patients referred to a clinical laboratory in Tehran, Iran, in ۲۰۱۹.Methods: We evaluated anti-HP IgA and IgG antibodies using the ELISA method. Positive and negative results were analyzed. During this study, we examined a total of ۵۹۳ patients who were referred to clinical laboratories due to symptoms of the disease. We collected serum samples from these patients and used them for diagnosis via an ELISA kit.Results: Out of ۵۹۳ patients, ۴۵۱ tested positive for both antibodies. Additionally, ۸۷% of patients tested positive for IgG, and ۴۷.۸% tested positive for IgA. The findings also demonstrated that among different age groups, patients above ۷۰ years old had the highest percentage of positive results for IgG (۹۰%), while the age group of ۵۰–۶۰ years old had the highest percentage of positive results for IgA (۸۲%). There were no statistically significant differences between the genders.Conclusion: It seems that the number of patients suffering from this disease is increasing in Tehran, and even younger age groups are now being affected. For a reliable diagnosis, the evaluation of both antibodies is recommended.

کلیدواژه ها:

Antibody ، ELISA ، Epidemiology ، Helicobacter pylori