Magnesium Status and Supplementation in Children With Attention-deficit/Hyperactivity Disorder: A Systematic Review

Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition that can have major effects on the affected individual’s personal and social life. Complementary treatments, including nutritional supplements, can help improve the symptoms of patients with ADHD. Therefore, this review study investigated magnesium deficiency in children with ADHD and the effectiveness of this mineral supplement. Methods: This paper systematically reviewed the literature available in Google Scholar, PubMed, and Scopus databases. Studies focusing on children with ADHD published in English were selected without any time limitations, up to December ۲۰۲۳. From a comprehensive review of ۱,۱۱۵ publications, eight articles were carefully selected for inclusion in the study.  Results: Selected descriptive studies have demonstrated a correlation between ADHD and reduced levels of magnesium in children’s serum and hair compared to their healthy counterparts. Furthermore, magnesium supplementation is an effective means of mitigating the symptoms associated with this disorder. Conclusions: According to recent research, magnesium micronutrient has shown potential in alleviating the symptoms associated with ADHD. This is attributed to its pivotal role in the central nervous system. Given its significance in regulating neurotransmitters and synaptic plasticity, magnesium is a valuable addition to the existing treatment options for ADHD. Further studies are warranted to fully elucidate its efficacy and potential side effects. Nonetheless, the findings thus far are promising and merit consideration by healthcare professionals.

کلیدواژه ها:

Attention-deficit/hyperactivity disorder (ADHD) ، Magnesium ، Nutrition