Prevalence of tuberculosis/COVID ۱۹ co-infection among active tuberculosis patients at a tertiary care hospital in Uttarakhand, India

Coronavirus disease ۲۰۱۹ (COVID-۱۹) was spread all over the world and was accepted as a pandemic by the World Health Organization (WHO) on March ۱۱, ۲۰۲۰. Lungs are predominantly affected by tuberculosis and Covid-۱۹. The objective of the study was to assess the clinical features of COVID-۱۹ in active tuberculosis (pulmonary and extra-pulmonary) and to identify the radiological and laboratory picture of COVID ۱۹ in patients with active tuberculosis. A cross sectional study was by the Department of Respiratory Medicine, Himalayan Institute of Medical Sciences, among patients of active tuberculosis (pulmonary and extra-pulmonary) presented to the General Outpatient Department(OPD) of the Respiratory Medicine Department. The questionnaire included questions on socio demographic profile, clinical features, comorbidities, clinical history, any substance abuse and laboratory investigations. Data was analyzed by SPSS software version ۲۱.۰ while Chi- square test was used for categorical data analysis. The mean age of the study participants was ۴۷.۵±۵.۳ years (Range ۱۸-۷۲). Males constituted the larger group (۵۹.۳۸%) as compared to females (۴۰.۶۳%). The prevalence of COVID۱۹/tuberculosis co-infection in the present study was ۲۱.۸%. Positive history of contact, bacterial culture, PCR and CBNAAT, use of drug, presence of cavity and pleural effusion on X Ray, showed all remarkably higher chances (p< ۰.۰۵) of developing co-infection. The prevalence of COVID۱۹/tuberculosis co-infection in the present study was high. Significantly associated factors can help in identifying Covid ۱۹ infection among tuberculosis patients. Therefore, it is recommended that screening for these factors should be done for all the tuberculosis patients coming for treatment and Covid ۱۹ vaccination.

کلیدواژه ها:

Lung ، Xray ، Pleural effusion ، History ، addiction