Evaluation of the co -occurrence of polycystic ovarian morphology and uterine anomalies in infertile women: a cross -sectional study

Polycystic ovarian syndrome (PCOS) is a lifelong, prevalent endocrine disorder affecting reproductive -aged women. Previous studies have suggested a potential link between PCOS and Müllerian anomalies. Based on Rotterdam criteria diagnosis of PCOS requires the presence of two out of the following three criteria: ovulatory dysfunction, clinical or biochemical signs of hyperandrogenism, and polycystic ovary morphology (PCOM). PCOM is defined as the presence of an ovarian volume > ۱۰ mL or ۱۲ or more follicles measuring ۲-۹ mm in size. This cross-sectional study aimed to determine the prevalence of PCOM among infertile women with uterine anomalies attending the Royan Research Institute in Tehran, Iran, between January ۲۰۲۱ and December ۲۰۲۲. A cohort of ۸۸۴ infertile women undergoing ۳D-hysterosonography were enrolled in the study and categorized into two groups: ۱۲۷ with uterine anomalies and ۷۵۷ without. Data extracted from medical records revealed a significantly higher frequency of PCOM in women with uterine anomalies (۴۰.۹%, ۵۲ women) compared to those without (۱۴.۷%, ۱۱۱ women) (p=۰.۰۰۰۱). Understanding the link between uterine abnormalities and PCOM is crucial for improving infertility management. Infertility treatment providers should pay close attention to this aspect when creating and implementing treatment plans.

کلیدواژه ها:

Uterine abnormalities ، Polycystic ovary morphology (PCOM) ، Mullerian anomalies