Investigation of the Effect of isocyanate type on adhesion and biological properties of castor oil-based polyurethane bioadhesive

Bioadhesives are a superior alternative to sutures due to their characteristics, including enhanced biocompatibility and ease of application. Among the adhesives studied, polyurethane-based bioadhesive is the best option for medical applications due to its structural and engineering advantages for environmental health. In this study, air-cure polyurethane bioadhesives were synthesized by pre-polymerization methods based on castor oil (CO) as soft segments and Hexamethylene diisocyanate (HDI) and Isophorone diisocyanate (IPDI) as hard segments, and the effect of hard segments' composition on adhesion strength of polyurethane bioadhesives was investigated.

کلیدواژه ها:

Isocyanate ، Bioadhesive ، Polyurethane ، air cure ، synthesis