Comparative effects of Eccentric Quasi -Isometric exercise with and without Blood Flow -Restrict ion, and Conventional Resistance training on Delayed -Onset Muscle Soreness , knee Range Of Motion and Creatine Kinase serum levels in Trained Men

Introduction. This study compared the effects of eccentric quasi -isometric (EQI) alone, with blood flow - restricted (EQI+BFR), and conventional resistance training with BFR ( RT+BFR) on delayed -onset muscle soreness (DOMS), knee range of motion (ROM) and serum level of creatine kinase (CK) in trained men. Methodology. Twenty -four resistance -trained males (age ۲۲.۵ ± ۱.۳ years; BMI ۲۲.۶ ± ۱.۶ kg/m²) were randomly assigned to three groups (n = ۸ each): EQI, EQI+BFR, and RT+BFR. All participants performed four sets of leg extensions at ۷۰% of one -repetition maximum. BFR bands were inflated to ۱۶۷ ± ۱۱ mmHg in the EQI+BFR and RT+BFR groups. DOMS was evaluated via a ۱۰۰ -mm Visual Ana logue Scale and quadriceps range of motion at pre - exercise and ۲۴, ۴۸, and ۷۲ hours post -exercise. Blood samples collected at the same time points were analyzed for creatine kinase. Data were examined using repeated -measures ANOVA with Bonferroni post hoc tests. Discussion. All groups experienced significant time -dependent increases in DOMS and creatine kinase serum levels, peaking between ۲۴ and ۴۸ hours before trending toward baseline by ۷۲ hours. No significant differences emerged among EQI, EQI+BFR, and RT+BFR groups for VAS scores (p = ۰.۴۷۳), range of motion (p = ۰.۱۸۹), creatine kinase (p = ۰.۵۶۳). Conclusion. Among trained men performing moderate -intensity leg extensions, eccentric quasi -isometric, whether combined with blood flow -restriction or not, and conventional resistance training with BFR protocols induced comparable DOMS and muscle damage responses. Incorporating BFR into EQI exercise neither amplified nor mitigated muscle soreness or indicators of damage. Future research should employ larger samples, higher intensities, and extended follow -up periods to clarify potential differential effects.

کلیدواژه ها:

Eccentric Quasi -Isometric ، Blood Flow Restriction ، Muscle Soreness