Background and Aims: Traditional teaching methods in medical education, especially in skill-based programs like physiotherapy, face challenges such as limited interaction, low motivation, and a lack of practical exercises. These limitations have led to the adoption of innovative approaches, such as gamification, to enhance learning. This study aims to design and evaluate a gamified educational application for the 'Physiotherapy in Neurological Patients' course within the undergraduate physiotherapy program. Methods: This participatory qualitative study was conducted in ۲۰۲۳–۲۰۲۴ in collaboration with experts in physiotherapy, medical education, medical informatics, and programming. The app's architecture was developed based on a literature review and expert consultations to address the educational needs of the 'Neurological Physiotherapy' course. Educational content was created and validated, including text, images, and video materials. The final app incorporated gamification elements like points, levels, challenges, and feedback. Usability was evaluated using the think-aloud method with physiotherapy students. Results: The content was reviewed by four physiotherapy professors, and seven physiotherapy students evaluated it positively for comprehensiveness (۹۱%), simplicity (۸۲%), and relevance (۹۱%). The PhysioMaster app includes two panels (admin and student), interactive questions, a leaderboard, immediate and final feedback, and case-based scenarios. Technical evaluations revealed issues with login functionality and score calculation errors, while usability tests identified problems with the layout and progress bar display. These issues were resolved before the final version of the app was released. Conclusion: This study focuses on designing and evaluating the game-based educational app 'PhysioMaster' for physiotherapy in neurological patients. The app offers gamified content based on the official curriculum and local needs and provides a simulated environment for practical practice. Future research should evaluate the app's effectiveness as an educational intervention using quasi-experimental or interventional designs and explore the potential for expanding this educational model to other areas of medical education.
