An overview of recombinant vaccines against viral, fungal, bacterial and parasitic diseases

سال انتشار: 1403
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 251

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شناسه ملی سند علمی:

JR_IJHES-2-4_004

تاریخ نمایه سازی: 28 تیر 1404

چکیده مقاله:

In the present era, particularly with the outbreak of infectious diseases including viral, fungal, parasitic, and bacterial infections, the need for designing and producing vaccines has become more critical than ever. Vaccination is one of the greatest public health achievements of the past century, protecting and improving the quality of life for people worldwide. Recombinant vaccines, produced using recombinant DNA technology, are discussed in this study. The microorganisms causing infections in humans, birds, and animals include adenovirus, infectious laryngotracheitis virus, human papillomavirus, Brucella and Listeria, Candida, Aspergillus, Cryptococcus, and Listeria. Vaccination is a highly effective strategy for controlling these types of diseases, making the acceleration of vaccine development essential for combating these diseases. Since one of the main factors contributing to the increased frequency and severity of diseases is the lack of cellular or humoral immunity, vaccine strategies must be safe and effective in hosts with both healthy and compromised immune systems. Advances in proteomics and systems biology have facilitated the development of several proposed vaccines, particularly as these vaccines enable the localization of proteins and the description of their changes, functions, and interactions.In the present era, particularly with the outbreak of infectious diseases including viral, fungal, parasitic, and bacterial infections, the need for designing and producing vaccines has become more critical than ever. Vaccination is one of the greatest public health achievements of the past century, protecting and improving the quality of life for people worldwide. Recombinant vaccines, produced using recombinant DNA technology, are discussed in this study. The microorganisms causing infections in humans, birds, and animals include adenovirus, infectious laryngotracheitis virus, human papillomavirus, Brucella and Listeria, Candida, Aspergillus, Cryptococcus, and Listeria. Vaccination is a highly effective strategy for controlling these types of diseases, making the acceleration of vaccine development essential for combating these diseases. Since one of the main factors contributing to the increased frequency and severity of diseases is the lack of cellular or humoral immunity, vaccine strategies must be safe and effective in hosts with both healthy and compromised immune systems. Advances in proteomics and systems biology have facilitated the development of several proposed vaccines, particularly as these vaccines enable the localization of proteins and the description of their changes, functions, and interactions.

نویسندگان

Tala Hayati

Department of Microbiology.Faculty of Biological Sciences. Falavarjan Branch Islamic Azad University. Isfahan.Iran.

Neda Korkorian

Department of Microbiology.Faculty of Biological Sciences. Falavarjan Branch Islamic Azad University. Isfahan.Iran

Nazanin Pashotan

Department of Microbiology.Faculty of Biological Sciences. Falavarjan Branch Islamic Azad University. Isfahan.Iran

Maede Kiani

Department of Microbiology.Faculty of Biological Sciences. Falavarjan Branch Islamic Azad University. Isfahan.Iran

Hurie Sadat Hashemi Fesharaki

Department of Microbiology.Faculty of Biological Sciences. Falavarjan Branch Islamic Azad University. Isfahan.Iran

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