Paraquat Poisoning: Clinical Insights from a ۳۳-year-old Iranian Survivor with Lung Injury

سال انتشار: 1404
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 18

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شناسه ملی سند علمی:

JR_PJMT-14-2_006

تاریخ نمایه سازی: 2 تیر 1404

چکیده مقاله:

Introduction: Paraquat is one of the most widely used herbicides worldwide. It is quick-acting and non-selective, killing green plant tissue on contact. Paraquat poisoning is a critical condition with a high mortality rate due to its extreme toxicity, particularly with regard to its impact on lung health.Case Presentation: This case report delineates the clinical progression and therapeutic interventions for a ۳۳-year-old Iranian male who survived a substantial ingestion of paraquat, an occurrence that is frequently associated with deleterious outcomes. The patient was admitted following a suicide attempt involving paraquat, manifesting symptoms such as nausea, vomiting, and erythematous rashes. Despite receiving immediate and intensive treatment, including hemodialysis, antioxidant therapy, and comprehensive supportive care, the patient experienced acute lung injury on the fifth day of hospitalization, as confirmed by computed tomography (CT) scans.Discussion: This case underscores the critical importance of early intervention and ongoing monitoring in the management of paraquat poisoning, particularly in reducing the risk of severe complications like lung injury. While the patient was ultimately discharged in stable condition, the development of lung damage underscores the need for further research into more effective therapies for paraquat toxicity.Conclusion: This report contributes to the limited clinical knowledge surrounding paraquat poisoning, offering valuable insights for healthcare providers dealing with similar cases.

نویسندگان

Arman Hakemi

Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Farima Farsi

Obesity and eating habits research institute, Tehran University of Medical Sciences, Tehran, Iran

Alireza Ghassemi Toussi

Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran