Synthesis of Polyfunctionalized Pyrroles by a PPh۳-Promoted Condensation Reaction Between Ammonium Acetate, Dialkyl Acetylenedicarboxylate and Arylglyoxals

A simple and efficient synthesis of some polyfunctionalized pyrrole derivatives by a triphenylphosphine-promoted condensation reaction between dialkyl acetylenedicarboxylates, arylglyoxals, and ammonium acetate is described. This present  method carries several advantages, such as good yields, a simple procedure, non-hazardous reaction conditions and starting from easily accessible substrates

کلیدواژه ها:

Dialkyl acetylenedicarboxylates ، Triphenylphosphine ، Ammonium acetate ، Intramolecular Wittig reaction ، Arylglyoxals