Mononuclear and Dinuclear Copper(II) Complexes Containing N, O and S Donor Ligands: Synthesis, Characterization, Crystal Structure Determination and Antimicrobial Activity of [Cu(phen)(tda)].۲H۲O and [(phen)۲Cu(µ-tda)Cu(phen)](ClO۴)۲.۱.۵H۲O

Copper complexes of [Cu(phen)(tda)].۲H۲O(۱) and [(phen)۲Cu(µ-tda) Cu(phen)](ClO۴)۲.۱.۵H۲O (۲) (where phen is ۱,۱۰-phenanthroline and tda۲- is thiodiacetate) have been synthesized. Both complexes were characterized by elemental analysis, IR, UV–Vis spectroscopy and cyclic voltammetry. Their solid state structures were determined by the single crystal X-Ray Diffraction method. Complex ۱ is mononuclear and copper has accepted a five-coordinated square-based pyramidal structure with the tda۲- anion facially coordinated to copper(II). Complex ۲ has accepted an unsymmetrical square pyramidal coordination of two distinct copper complexes, one containing two phenanthroline and the other containing one phenanthroline and one tda۲-, bridged by a carboxylate oxygen. The strong biological activity of these compounds against six reference bacterial included Bacillus subtilis (ATCC ۴۶۵), Enterococcus faecalis (ATCC ۲۹۷۳۷), Staphylococcus aureus (ATCC ۲۵۹۲۳), Escherichia coli (ATCC ۲۵۹۲۲), Klebsiella pneumoniae (ATCC ۱۰۰۳۱), and Pseudomonas aeruginosa (ATCC ۸۵۳۲۷)  were investigated.

کلیدواژه ها:

Cu(II) complexes ، ۱ ، ۱۰-Phenanthroline ، Thiodiacetic acid ، Crystal structure ، Cyclic voltammogram. Antimicrobial activities