A Systematic Review of Therapeutic Potential of Illicit Drugs: A Narrative Overview of How Cannabinoids and Psychedelics Can be Used in Medicine

To aid the therapeutic process, illicit chemical substances and drugs are used in drug therapy. Various cultures have used illegal substances for thousands of years in medicine and various practices. The present study is a general approach to pharmaceutical science and attempts to contextualize drug-assisted therapy through an integrative literature review. All related articles were found through the electronic databases Medical Publications (Pubmed) and Scopus. The research question was related to articles written in English within the last ۲۰ years. The database research found ۷۷ articles on psychedelics between Jan ۲۰۰۰ and Oct ۲۰۲۱. Twenty-two articles were selected for analysis according to the inclusion criteria. In analyzing the texts, we have been able to correlate several aspects. We conclude that psychedelic therapy has great potential and that its rebirth occurs in the context of social transformations and demands in psychotherapy that are unmissable. Database searches between Jan ۲۰۰۰ and Oct ۲۰۲۱ found ۱۱۶۴ articles about cannabinoids. According to the inclusion criteria, only ۲۳۵ articles were selected for analysis. The United States produced the most publications, followed by Canada and Australia; evidence has steadily increased between ۲۰۰۰ and ۲۰۲۱. The contents of the publications deal with beneficial and adverse health effects, the consequences of cannabis legislation, and its association with various variables. There is a lack of research on cannabis' medicinal use regarding treatments and diseases, its standardization, routes of administration, and doses, recognizing the need for more research.

کلیدواژه ها:

Drug Therapy ، Psychedelic Therapy ، Psychedelic ، Psychedelic associated therapy ، Psychedelic drugs ، Cannabis-based drugs ، Cannabinoid therapy ، Cannabidiol